Any way to free hand crop an image?

How do you propose cropping a non-rectangular shape? Do you want to zero out parts that aren't within in your "cropped" region. An image always has to be rectangular.

doc imcrop
doc impoly
doc imfreehand

If you want to zero out the parts not in the free hand reason. use the createMask method of the freehand region to build a mask of the free hand region. Then negate it and zero everything in it out.

I = imread('cameraman.tif');
imshow(I);
h = imfreehand; %draw something 
M = ~h.createMask();
I(M) = 0;
imshow(I);